Sean Raspet in collaboration with Shengping Zheng's lab

Hyperflor© (2-benzyl-1,3-dioxan-5-one)

2018 – 2019

2-benzyl-1,3-dioxan-5-one molecule

The molecule 2-benzyl-1,3-dioxan-5-one was designed by Sean Raspet for its specific olfactory properties. It is a new molecule, having not previously existed in nature or in scientific literature prior to its creation in 2018. It was first synthesized in the lab of Shengping Zheng with help from Sihan Li, using a reaction pathway developed by Raspet.

The molecule has a patent pending and is currently in the process of commercialization for use in industrially produced fragrances and scented products under the trade name Hyperflor©.

Hyperflor© has been described as having a very strong floral aspect even in high dilution. Though it is entirely synthetic, it is perceived as more a more natural, complex and full scent than those of naturally occurring scent molecules found in most flowers. For the Okayama Art Summit, the molecule is diffused into the air in several locations throughout the city, often functioning as a "scene transition" between different spaces. Predictive models show that Hyperflor© can activate the BRA1 receptor in humans which is associated with anti-tumor activity and DNA repair. It shares structural features with certain plant root growth hormones such as phenylacetic acid may additionally have activity in plant metabolism.

special thanks to Sihan Li and Hunter College, CUNY